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Mitochondrial & metabolic signaling

AOD-9604

A synthetic 16-residue peptide: tyrosine followed by residues 177–191 of human growth hormone, with a disulfide bond between its two cysteines.

Also known as Tyr-hGH (177–191)

Formula
C78H123N23O23S2
Average mass
1815.082 Da
Length
16 residues
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Vial size

5 or 10 mg vials

Lot Loading the lot Record
  • Sealed, crimp-capped vial with its lot number on the label.
  • Orders are packed once payment clears.

Research use only. AOD-9604 is supplied as a laboratory reagent. It is not a drug, food, supplement or cosmetic, and it is not for human or veterinary use.

Lot record

Check the lot before you buy.

Purity is the main peak’s share of the HPLC signal. Identity is the mass the sequence predicts, next to the mass measured. Move along either trace to read it.

Certificate of analysis

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HPLC purity
Release minimum
99.0%
Mass, calculated
1815.082 Da
Mass, observed
Difference
release rule: within ±1.0 Da
Tested
Laboratory
Method

How to read a certificate
HPLC RP · UV 220 nm

The chromatogram draws here from the lot’s numbers.

Mass spec ESI, positive

The mass spectrum draws here from the sequence and the lot’s numbers.

Every published lot

Published lots of AOD-9604
LotTestedHPLC purityObserved mass, DaStatusCertificate

Overview

What it is.

AOD-9604 adds an N-terminal tyrosine to the C-terminal 15 residues of human growth hormone. Its two cysteines form an intramolecular disulfide bond (Cys7–Cys14), matching the loop at the C-terminal end of the native hormone, and the formula and masses shown include that bond.

It was developed as a drug candidate; clinical trials did not lead to an approved medicine. It is studied in cell and animal research on lipid metabolism.

We don’t summarize studies on product pages. Search PubMed for “AOD-9604” (opens in a new tab)

Sequence & properties

Computed from the sequence.

Y1L2R3I4V5Q6C7R8S9V10E11G12S13C14 G15F16

Residue colors: Hydrophobic Polar Basic (+) Acidic (−) Non-standard

Three-letter sequence: H-Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe-OH

Open in Sequence Studio
Molecular formula
C78H123N23O23S2
Average mass
1815.082 Da
Monoisotopic mass
1813.8604 Da
Length
16 residues
Isoelectric point (pI)
9.35
Net charge at pH 7.0
+0.98
GRAVY (Kyte–Doolittle)
+0.300
Extinction coefficient, 280 nm
1,615 M−1cm−1
Modifications
1 disulfide bond
CAS number
221231-10-3
Form
Lyophilized powder in a sealed glass vial
Purity
Measured per lot by HPLC: see the lot record

Calculated from the sequence with standard atomic weights and the EMBOSS pKa set, for the free peptide (not a salt form). The formula matches the PubChem entry for AOD-9604 (opens in a new tab); the mass agrees with it to within 0.05 Da.

HydropathyKyte–Doolittle · window 7
−4−20+2+4YLRIVQCRSVEGSCGF↑ HYDROPHOBIC−4−20+2+4YLRIVQCRSVEGSCGF↑ HYDROPHOBIC−4−20+2+4YLRIVQCRSVEGSCGF↑ HYDROPHOBIC

Above zero is hydrophobic; below is polar or charged. Most hydrophobic stretch: residues 4–10 (average +0.9). Most polar: residues 6–12 (average −0.9). Windows above zero: 5 of 10.

Storage & handling

Cold, dry and dark.

Sealed vial
Follow the released lot’s documented storage conditions and laboratory safety data.
In transit
Transport conditions must be supported for this material; ambient shipping is not assumed.
Before opening
Let the vial reach room temperature, so moisture doesn’t condense on the powder.
In solution
Use a validated in-vitro laboratory protocol. Stability depends on the compound, solvent and conditions; no general shelf life is promised.

Questions

Before you order.

All questions
How do I know what’s in the vial?

Every lot we sell has a certificate of analysis on file, showing HPLC purity and mass-spectrometry identity for that exact lot. It is linked on the product page before you buy.

The lot number printed on your vial opens the same record on our Verify page, so you can match the vial in your hand to its test results.

What does an HPLC purity figure tell me?

High-performance liquid chromatography separates a sample into its components. Purity is the main peak’s share of the total detected signal, usually measured by UV absorbance around 214–220 nm.

It measures the main component against peptide-related impurities; it isn’t net peptide content, which also accounts for water and counter-ions.

How do I pay, and when does my order ship?

The available payment methods are listed at checkout. A research request first enters review, with no payment due. Payment instructions appear only after verification and approval. Sample requests cannot be paid or fulfilled.

Orders are packed once payment clears. You can follow every step on the order page or with your order number on Track an order.

What does “research use only” mean?

Our peptides are supplied as laboratory reagents for research by qualified buyers. None is approved as a drug, food, supplement or cosmetic in the form we supply it, and none is for human or veterinary use.

We don’t give advice about using peptides in people or animals, and product pages describe what each compound is and how it is studied, never what it does to a person.

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5 mg vial